Antibiotics didn't clear up my wisdom tooth infection she prescribed a week's course of antibiotics. This is when iv antibiotics or extraction are needed. Pin On Healthy Teeth The only way to solve it at that point is for a dentist to get in there and physically remove the infected tissue. Wisdom tooth infection antibiotics not working . However, dental infection often completely destroys the blood vessels that supply the inside of the tooth. You’ll need to take antibiotics to clear up an infection in a wisdom tooth. However, that doesn't mean that your infection is cured. For others, you’ll need to visit an emergency dentist for treatment of the infected tooth. I found that corsodyl stuff was fantastic though if you use it correctly, it says not to use it straight after brushing your teeth because something in the toothpaste stops it working effectively. The swelling in my face is worse today than it was yesterday. You must make sure to take your an...